供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL7862R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 上皮分泌型FAM3C蛋白抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed上皮分泌型FAM3C蛋白抗体 mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates上皮分泌型FAM3C蛋白抗体 with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.
上皮分泌型FAM3C蛋白抗体Also known as:
Fam3c; FAM3C_HUMAN; family with sequence similarity 3, member C; GS3786; ILEI; Interleukin-like EMT inducer; Predicted osteoblast protein; Protein FAM3C.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .
●
Immunogen: KLH conjugated synthetic peptide derived from human FAM3C.
●
Predicted Molecular Weight: 22kDa.
上皮分泌型FAM3C蛋白抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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