表皮细胞表面抗原1/Esa1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 表皮细胞表面抗原1/Esa1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Lipid rafts are sphingolipid- and cholesterol-rich membrane microdomains that are insoluble in nonionic detergents. Lipid rafts are important for numerous cellular processes, including signal transduction, membrane trafficking and molecular sorting. Flotillins are lipid raft components in neurons and caveloae-associated proteins in A498 kidney cells. Flotillin-2, 表皮细胞表面抗原1/Esa1抗体also designated epidermal surface antigen, is conserved in all mammalian species. Flotillin-1 and -2 have complementary tissue distributions and their expression levels are independently regulated. At the cellular level, Flotillin-2 is ubiquitously expressed, whereas Flotillin-1 is expressed in A498 kidney cells, muscle cell lines and fibroblasts. Stable transfection of 表皮细胞表面抗原1/Esa1抗体a Flotillin-2 fusion protein in COS cells induces filopodia formation and changes epithelial cells to a neuronal appearance. Flotillins form a ternary complex with CAP and Cbl, directing the localization of the CAP-Cbl complex to a lipid raft subdomain of the plasma membrane. Association of ER-X with Flotillin localizes ER-X within plasma membrane caveloae and mediates rapid oestrogen activation of the MAP kinase cascade. The expression of the flotillins is also correlated to the progression of Alzhemier pathology.

表皮细胞表面抗原1/Esa1抗体Also known as:

ECS-1; ECS1; Epidermal surface antigen 1; Epidermal surface antigen; ESA; ESA1; Flot2; FLOT2_HUMAN; Flotillin-2; M17S1 antibody Membrane component chromosome 17 surface marker 1; Membrane component chromosome 17 surface marker 1 homolog; Membrane component, chromosome 17, surface marker 1; REG-1; Reggie-1; Reggie-2.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human ECS1.

●

Predicted Molecular Weight: 47kDa.

表皮细胞表面抗原1/Esa1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl472Mu01降钙素(CT)多克隆抗体Polyclonal Antibody to Calcitonin (CT)

kl472Ra01降钙素(CT)多克隆抗体Polyclonal Antibody to Calcitonin (CT)

kl473Hu01C组着色性干皮病偶联因子(XPC)多克隆抗体Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group C (XPC)

kl473Mu01C组着色性干皮病偶联因子(XPC)多克隆抗体Polyclonal Antibody to Xeroderma Pigmentosum, Complementation Group C (XPC)

kl474Hu01甲状旁腺素受体2(PTHR2)多克隆抗体Polyclonal Antibody to klathyroid Hormone Receptor 2 (PTHR2)

kl474Ra01甲状旁腺素受体2(PTHR2)多克隆抗体Polyclonal Antibody to klathyroid Hormone Receptor 2 (PTHR2)

kl475Hu01维生素D受体(VDR)多克隆抗体Polyclonal Antibody to Vitamin D Receptor (VDR)

kl475Mu01维生素D受体(VDR)多克隆抗体Polyclonal Antibody to Vitamin D Receptor (VDR)

kl476Hu01半胱氨酸蛋白酶抑制剂A(CSTA)多克隆抗体Polyclonal Antibody to Cystatin A (CSTA)

kl478Hu01心肌肌钙蛋白I(TNNI3)多克隆抗体Polyclonal Antibody to Troponin I Type 3, Cardiac (TNNI3)

kl478Mu01心肌肌钙蛋白I(TNNI3)多克隆抗体Polyclonal Antibody to Troponin I Type 3, Cardiac (TNNI3)

kl478Po01心肌肌钙蛋白I(TNNI3)多克隆抗体Polyclonal Antibody to Troponin I Type 3, Cardiac (TNNI3)

kl478Ra01心肌肌钙蛋白I(TNNI3)多克隆抗体Polyclonal Antibody to Troponin I Type 3, Cardiac (TNNI3)

kl480Po01肌红蛋白(MYO)多克隆抗体Polyclonal Antibody to Myoglobin (MYO)

kl483Hu01内皮素转化酶1(ECE1)多克隆抗体Polyclonal Antibody to Endothelin Converting Enzyme 1 (ECE1)

kl483Mu01内皮素转化酶1(ECE1)多克隆抗体Polyclonal Antibody to Endothelin Converting Enzyme 1 (ECE1)

kl484Hu01氨基端前心钠肽(NT-ProANP)多克隆抗体Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

kl484Mu01氨基端前心钠肽(NT-ProANP)多克隆抗体Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

kl484Ra01氨基端前心钠肽(NT-ProANP)多克隆抗体Polyclonal Antibody to N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

kl488Hu01角蛋白5(KRT5)多克隆抗体Polyclonal Antibody to Keratin 5 (KRT5)

kl489Hu01角蛋白4(KRT4)多克隆抗体Polyclonal Antibody to Keratin 4 (KRT4)

kl491Hu01角蛋白2(KRT2)多克隆抗体Polyclonal Antibody to Keratin 2 (KRT2)