供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL11269R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 类固醇受体复合物蛋白FKBP5抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin (1). Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin (2,3). The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, where it 类固醇受体复合物蛋白FKBP5抗体stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4). FKBP51 and FKBP52 are two highly related proteins (5,6). FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5). FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation (7). FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
类固醇受体复合物蛋白FKBP5抗体Also known as:
FKBP 5; FKBP 51; FKBP 54; FKBP-5; FKBP-51; FKBP5; FKBP5_HUMAN; FKBP54; HSP90 binding immunophilin; HSP90-binding immunophilin; P54 antibody Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; Peptidylprolyl cis trans isomerase; PPIase; PPIase FKBP5; Ptg 10; Ptg10; Rotamase; T cell FK506 binding protein; 51 kDa FK506 binding protein 5; 类固醇受体复合物蛋白FKBP5抗体51 kDa FK506 binding protein; 51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor associated immunophilin; 54 kDa progesterone receptor-associated immunophilin; AIG 6; AIG6; Androgen regulated protein 6; Androgen-re
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human FKBP51.
●
Predicted Molecular Weight: 51kDa.
类固醇受体复合物蛋白FKBP5抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl492Hu01角蛋白1(KRT1)多克隆抗体Polyclonal Antibody to Keratin 1 (KRT1)
kl500Hu01嵌套蛋白(NES)多克隆抗体Polyclonal Antibody to Nestin (NES)
kl512Hu01纤维介素蛋白(FGL2)多克隆抗体Polyclonal Antibody to Fibrinogen Like Protein 2 (FGL2)
kl512Mu01纤维介素蛋白(FGL2)多克隆抗体Polyclonal Antibody to Fibrinogen Like Protein 2 (FGL2)
kl514Hu01失调蛋白1(ATXN1)多克隆抗体Polyclonal Antibody to Ataxin 1 (ATXN1)
kl516Hu01角蛋白16(KRT16)多克隆抗体Polyclonal Antibody to Keratin 16 (KRT16)
kl517Hu01角蛋白15(KRT15)多克隆抗体Polyclonal Antibody to Keratin 15 (KRT15)
kl520Hu01蛋白激酶R(PKR)多克隆抗体Polyclonal Antibody to Protein Kinase R (PKR)
kl522Hu01角蛋白14(KRT14)多克隆抗体Polyclonal Antibody to Keratin 14 (KRT14)
kl524Hu01组织因子(TF)多克隆抗体Polyclonal Antibody to Tissue Factor (TF)
kl524Mu01组织因子(TF)多克隆抗体Polyclonal Antibody to Tissue Factor (TF)
kl524Po01组织因子(TF)多克隆抗体Polyclonal Antibody to Tissue Factor (TF)
kl524Ra01组织因子(TF)多克隆抗体Polyclonal Antibody to Tissue Factor (TF)
kl524Rb52组织因子(TF)多克隆抗体Polyclonal Antibody to Tissue Factor (TF)
kl525Hu01组织型纤溶酶原激活因子(tPA)多克隆抗体Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)
kl525Mu01组织型纤溶酶原激活因子(tPA)多克隆抗体Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)
kl525Po01组织型纤溶酶原激活因子(tPA)多克隆抗体Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)
kl525Ra01组织型纤溶酶原激活因子(tPA)多克隆抗体Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)
kl528Ra01血小板衍生生长因子A(PDGFA)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Subunit A (PDGFA)
kl528Rb51血小板衍生生长因子A(PDGFA)多克隆抗体Polyclonal Antibody to Platelet Derived Growth Factor Subunit A (PDGFA)
kl529Ca01血栓调节蛋白(TM)多克隆抗体Polyclonal Antibody to Thrombomodulin (TM)
相关产品
关注
拨打电话
留言咨询