IgG-Fc片断受体转运蛋白α抗体

Quantity size:

0.2ml

Concentration:

1mg/ml IgG-Fc片断受体转运蛋白α抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn ? chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavyIgG-Fc片断受体转运蛋白α抗体 chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

IgG-Fc片断受体转运蛋白α抗体Also known as:

Alpha chain; Fc fragment of IgG, receptor transporter, alpha; FCGRN_HUMAN; FCGRT; FcRn alpha chain; FCRN; FCRN, alpha chain; IgG Fc fragment receptor transporter alpha chain; IgG Gc receptor; IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51 precursor; Immunoglobulin receptor, intestinal, heavy chain; Neonatal Fc receptor.

Specificity:

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Rabbit Polyclonal IgG, IgG-Fc片断受体转运蛋白α抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human FCGRT/Fc.

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Predicted Molecular Weight: 37kDa.

IgG-Fc片断受体转运蛋白α抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-200  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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