免疫球蛋白E受体Fc ε RIγ抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 免疫球蛋白E受体Fc ε RIγ抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

IgE Fc Receptor I binds to the Fc region of immunoglobulins epsilon chain with high affinity, and is responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators such as histamines, responsible免疫球蛋白E受体Fc ε RIγ抗体 for the manifestations of allergy. IgE Fc Receptor I also induces the secretion of important lymphokines, effectors of the hypersensitivity response. It is a tetramer of a heavily glycosylated alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chains from Fc epsilon RI are also subunits of other Fc receptors. The gamma subunit is thought to be functionally significant in allowing the IgE Fc receptor to reach the cell surface. 免疫球蛋白E受体Fc ε RIγ抗体The cytoplasmic domains of the beta and gamma subunits each contain a conserved consesus sequence, ITAM, (immunoreceptor tyrosine activation motif). Phosphorylation of a pair of conserved tyrosine residues within this motif is required for signal transduction in mast cells and other hemopoietic cell types.

Also known as:

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma chain; Fc-epsilon RI-gamma; FCER1G; FCERG_HUMAN; FceRI gamma; FCRG; FcRgamma; High affinity immunoglobulin 免疫球蛋白E受体Fc ε RIγ抗体epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; Immunoglobulin E receptor, high affinity, gamma chain.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .

●

Immunogen: KLH conjugated synthetic peptide derived from human FCER1G.

●

Predicted Molecular Weight: 10kDa.

免疫球蛋白E受体Fc ε RIγ抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl186Hu01肝细胞生长因子受体(HGFR)多克隆抗体Polyclonal Antibody to Heklocyte Growth Factor Receptor (HGFR)

kl192Hu01Axis抑制蛋白2(AXIN2)多克隆抗体Polyclonal Antibody to Axis Inhibition Protein 2 (AXIN2)

kl195Hu01分拣连接蛋白13(SNX13)多克隆抗体Polyclonal Antibody to Sorting Nexin 13 (SNX13)

kl196Hu01连接桥粒斑珠蛋白(JUP)多克隆抗体Polyclonal Antibody to Junction Plakoglobin (JUP)

kl200Ra01早老素1(PSEN1)多克隆抗体Polyclonal Antibody to Presenilin 1 (PSEN1)

kl202Hu01桥粒芯糖蛋白2(DSG2)多克隆抗体Polyclonal Antibody to Desmoglein 2 (DSG2)

kl203Hu01桥粒斑蛋白(DSP)多克隆抗体Polyclonal Antibody to Desmoplakin (DSP)

kl206Hu01组蛋白脱乙酰基酶1(HDAC1)多克隆抗体Polyclonal Antibody to Histone Deacetylase 1 (HDAC1)

kl210Hu01组蛋白脱乙酰基酶2(HDAC2)多克隆抗体Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)

kl210Mu01组蛋白脱乙酰基酶2(HDAC2)多克隆抗体Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)

kl216Hu01E1A结合蛋白P300(EP300)多克隆抗体Polyclonal Antibody to E1A Binding Protein P300 (EP300)

kl220Hu01博来霉素水解酶(BLMH)多克隆抗体Polyclonal Antibody to Bleomycin Hydrolase (BLMH)

kl221Hu01早幼粒细胞白血病蛋白(PML)多克隆抗体Polyclonal Antibody to Promyelocytic Leukemia Protein (PML)

kl228Hu01密封蛋白(OCLN)多克隆抗体Polyclonal Antibody to Occludin (OCLN)

kl228Mu01密封蛋白(OCLN)多克隆抗体Polyclonal Antibody to Occludin (OCLN)

kl228Ra01密封蛋白(OCLN)多克隆抗体Polyclonal Antibody to Occludin (OCLN)

kl232Hu01C-Raf原癌基因丝苏氨酸蛋白激酶(CRAF)多克隆抗体Polyclonal Antibody to C-Raf Proto Oncogene Serine/Threonine Protein Kinase (CRAF)

kl233Hu01抑丝蛋白1(PFN1)多克隆抗体Polyclonal Antibody to Profilin 1 (PFN1)

kl239Hu01甲状腺素受体α(THRα)多克隆抗体Polyclonal Antibody to Thyroid Hormone Receptor Alpha (THRa)

kl239Ra01甲状腺素受体α(THRα)多克隆抗体Polyclonal Antibody to Thyroid Hormone Receptor Alpha (THRa)

kl241Hu01端粒酶逆转录酶(TERT)多克隆抗体Polyclonal Antibody to Telomerase Reverse Transcriptase (TERT)

kl242Hu01核仁素(NCL)多克隆抗体Polyclonal Antibody to Nucleolin (NCL)