CD344抗体

Quantity size:

0.2ml

Concentration:

1mg/ml CD344抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Frizzled-4 is a 537 amino acid protein encoded by the human gene FZD4. Frizzled-4 acts as a receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt CD344抗体target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Frizzled-4 may be involved in transductionCD344抗体 and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Frizzled-4 also plays a critical role in retinal angiogenesis. Frizzled-4 is virtually ubiquitously expressed with greatest amounts found in adult heart, skeletal muscle, ovary, and fetal kidney.

CD344抗体Also known as:

CD 344; CD 344 antigen; CD344; CD344 antigen; EVR1; FEVR; Frizzled (Drosophila) homolog 4; Frizzled 4; Frizzled family receptor 4; Frizzled homolog 4 (Drosophila); Frizzled-4; Fz 4; Fz-4; Fz4; FZD4; FZD4_HUMAN; FZD4S; FzE4; GPCR; hFz4; MGC34390; WNT receptor frizzled 4.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Frizzled.

●

Predicted Molecular Weight: 56kDa.

CD344抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl625Hu01N-甲基嘌呤DNA糖基化酶(MPG)多克隆抗体Polyclonal Antibody to N-Methylpurine DNA Glycosylase (MPG)

kl629Hu01单酰甘油-O-酰基转移酶2(MOGAT2)多克隆抗体Polyclonal Antibody to Monoacylglycerol-O-acyltransferase 2 (MOGAT2)

kl650Hu01黑素瘤抑制性活性蛋白1(MIA1)多克隆抗体Polyclonal Antibody to Melanoma Inhibitory Activity Protein 1 (MIA1)

kl650Ra01黑素瘤抑制性活性蛋白1(MIA1)多克隆抗体Polyclonal Antibody to Melanoma Inhibitory Activity Protein 1 (MIA1)

kl662Hu01镍纹蛋白(METRN)多克隆抗体Polyclonal Antibody to Meteorin (METRN)

kl662Mu01镍纹蛋白(METRN)多克隆抗体Polyclonal Antibody to Meteorin (METRN)

kl663Hu01甲硫氨酰氨肽酶2(METAP2)多克隆抗体Polyclonal Antibody to Methionyl Aminopeptidase 2 (METAP2)

kl669Hu01NADP依赖性苹果酶2(ME2)多克隆抗体Polyclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2)

kl673Hu01苹果酸脱氢酶1(MDH1)多克隆抗体Polyclonal Antibody to Malate Dehydrogenase 1 (MDH1)

kl676Hu01MYC关联因子X(MAX)多克隆抗体Polyclonal Antibody to MYC Associated Factor X (MAX)

kl682Hu01微管关联丝/苏氨酸激酶2(MAST2)多克隆抗体Polyclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2)

kl688Hu01十四烷基化丙氨酸丰富蛋白激酶C底物(MARCKS)多克隆抗体Polyclonal Antibody to Myristoylated Alanine Rich Protein Kinase C Substrate (MARCKS)

kl705Hu01淋巴细胞抗原96(LY96)多克隆抗体Polyclonal Antibody to Lymphocyte Antigen 96 (LY96)

kl709Hu01胶乳素(LXN)多克隆抗体Polyclonal Antibody to Latexin (LXN)

kl716Hu01亮氨酸丰富重复激酶2(LRRK2)多克隆抗体Polyclonal Antibody to Leucine Rich Repeat Kinase 2 (LRRK2)

kl723Hu01亮氨酰/半胱氨酰氨肽酶(LNPEP)多克隆抗体Polyclonal Antibody to Leucyl/Cystinyl Aminopeptidase (LNPEP)

kl730Hu01甘露糖结合凝集素2(LMAN2)多克隆抗体Polyclonal Antibody to Lectin, Mannose Binding 2 (LMAN2)

kl755Hu01犬尿氨酸-3-单加氧酶(KMO)多克隆抗体Polyclonal Antibody to Kynurenine-3-Monooxygenase (KMO)

kl756Hu01可罗索β(KLβ)多克隆抗体Polyclonal Antibody to Klotho Beta (KLb)

kl756Mu01可罗索β(KLβ)多克隆抗体Polyclonal Antibody to Klotho Beta (KLb)