FBXW10蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml FBXW10蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulationFBXW10蛋白抗体 of a wide variety of cellular processes, including the cell cycle, immune responses, signaling cascades and developmental events, through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I?B-? and ∫-catenin, for proteasomal degradation. FBXW10 (F-box and WD FBXW10蛋白抗体repeat domain containing 10), also known as protein Ubiquitin ligase-specificity factor, is a 1,052 amino acid protein that contains one F-box domain and seven WD repeats. Existing as four alternatively spliced isoforms, FBXW10 induces degradation of CBX5 and CBX1.

FBXW10蛋白抗体Also known as:

F-box and WD-40 domain-containing protein 10; F-box/WD repeat-containing protein 10; FBW10_HUMAN; FBXW10; Ubiquitin ligase-specificity factor.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, .

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Immunogen: KLH conjugated synthetic peptide derived from human FBXW10.

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Predicted Molecular Weight: 120kDa.

FBXW10蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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