细胞外基质蛋白FREM2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 细胞外基质蛋白FREM2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

FREM2 is a 3,169 amino acid single-pass type I membrane protein that localizes to the extracellular side of the cell membrane and contains five Calx-beta domains, as well as 12 CSPG repeats.细胞外基质蛋白FREM2抗体 Functioning as an extracellular matrix protein, FREM2 is required for the maintenance of skin and renal epithelia and is also thought to be involved in epidermal adhesion events. Defects or mutations in the gene encoding FREM2, which maps to human chromsome 13, are associated with Fraser syndrome, a multisystem malformation that is characterized by ear abnormalities,细胞外基质蛋白FREM2抗体 congenital heart defects and cutaneous syndactyly. FREM2 exists as multiple alternatively spliced isoforms.

Also known as:

DKFZp781I048; ECM3 homolog; FRAS1-related extracellular matrix protein 2; FREM 2; Frem2; FREM2_HUMAN; KIAA1074.

细胞外基质蛋白FREM2抗体Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human FREM2.

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Predicted Molecular Weight: 346kDa.

细胞外基质蛋白FREM2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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