促代谢型谷氨酸受体2+4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 促代谢型谷氨酸受体2+4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic 促代谢型谷氨酸受体2+4抗体conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

促代谢型谷氨酸受体2+4抗体Also known as:

Metabotropic Glutamate Receptor 2+4; GRM2+GRM4; GRM2 + GRM4; GRM2/GRM4; GPRC1B; GPRC1D; GRM2; GRM4; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 4; mGluR2; mGluR4; GRM2_HUMAN; GRM4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 促代谢型谷氨酸受体2+4抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human GRM2+GRM.

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Predicted Molecular Weight: 102kDa.

促代谢型谷氨酸受体2+4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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