G蛋白偶联受体激酶相互作用蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml G蛋白偶联受体激酶相互作用蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell G蛋白偶联受体激酶相互作用蛋白1抗体surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).

G蛋白偶联受体激酶相互作用蛋白1抗体Also known as:

ARF GAP GIT1; ARF GTPase activating protein GIT1; CAT 1; Cat1; Cool associated and tyrosine phosphorylated protein 1; G protein coupled receptor kinase interactor 1; GRK interacting protein 1.

Specificity:

●

Rabbit Polyclonal IgG,G蛋白偶联受体激酶相互作用蛋白1抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, .

●

Immunogen: KLH conjugated synthetic peptide derived from human GIT1.

●

Predicted Molecular Weight: 84kDa.

G蛋白偶联受体激酶相互作用蛋白1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl371Mu0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl371Ra0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl373Hu01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl373Mu01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl373Ra01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl374Ra01GATA结合蛋白4(GATA4)多克隆抗体Polyclonal Antibody to GATA Binding Protein 4 (GATA4)

kl376Hu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl376Mu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl380Bo01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Hu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Mu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Ra01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl382Hu01蛋白激酶Bγ(PKBγ)多克隆抗体Polyclonal Antibody to Protein Kinase B Gamma (PKBg)

kl383Hu01磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗体Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)

kl383Mu01磷酸肌醇-3-激酶2α肽(PI3K2α)多克隆抗体Polyclonal Antibody to Phosphoinositide-3-Kinase Class-2-Alpha Polypeptide (PIK3C2a)

kl384Hu01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl384Mu01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl384Ra01白介素23(IL23)多克隆抗体Polyclonal Antibody to Interleukin 23 (IL23)

kl385Hu01白介素27(IL27)多克隆抗体Polyclonal Antibody to Interleukin 27 (IL27)

kl385Ra01白介素27(IL27)多克隆抗体Polyclonal Antibody to Interleukin 27 (IL27)

kl389Mu01补体成分4a(C4a)多克隆抗体Polyclonal Antibody to Complement Component 4a (C4a)

kl389Ra01补体成分4a(C4a)多克隆抗体Polyclonal Antibody to Complement Component 4a (C4a)

kl391Hu01卵泡抑素(FS)多克隆抗体Polyclonal Antibody to Follistatin (FS)

kl391Mu01卵泡抑素(FS)多克隆抗体Polyclonal Antibody to Follistatin (FS)