谷氨酰胺合成酶/谷氨酸氨连接酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 谷氨酰胺合成酶/谷氨酸氨连接酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the谷氨酰胺合成酶/谷氨酸氨连接酶抗体 multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also 谷氨酰胺合成酶/谷氨酸氨连接酶抗体decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.

Also known as:

GLNA; GLNS; GLUL; Gl Syn; glutamate-ammonia ligase; glutamine synthetase; GS; PIG 43; PIG 59; PIG43; PIG59; Proliferation inducing protein 43.

Specificity:

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Rabbit Polyclonal IgG, 谷氨酰胺合成酶/谷氨酸氨连接酶抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human Gl Syn.

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Predicted Molecular Weight: 42kDa.

谷氨酰胺合成酶/谷氨酸氨连接酶抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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