G蛋白偶联受体124抗体

Quantity size:

0.2ml

Concentration:

1mg/ml G蛋白偶联受体124抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Tumor endothelial markers (TEMs) display elevated expression during angiogenesis. Their associations with the cell surface membrane are of great interest for both biological and clinical research. G protein coupled receptor 124 (GPR124) is encoded as a seven pass transmembrane protein of 1331 amino acids and is most similar to the cadherin related Celsr1 proteins and members of the calcium independent alpha latrotoxin receptorG蛋白偶联受体124抗体 family involved in transmitting signals across the cell membrane. GPCRs have been excellent drug targets because their natural ligands can often mimicked for agonistic or antagonistic purpose. The existence of tumour specific endothelial markers provides a resource for further understanding the mechanisms of tumour angiogenesis and encourages the development G蛋白偶联受体124抗体of antiangiogenic therapies in the future. ESTs for the gene that encodes GPR124 have been isolated primarily from amnion, connective tissue, ear, embryo, eye, ganglion, heart, lung, placenta, and skin libraries.

Also known as:

TEM5; DKFZp434C211; DKFZp434J0911; FLJ14390; G protein coupled receptor 124; G-protein coupled receptor 124; GP124_HUMAN; GPR 124; GPR124; KIAA1531; TEM 5; TEM5; Tumor endothelial marker 5; G蛋白偶联受体124抗体Tumor endothelial marker 5 precursor.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human GPR124.

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Predicted Molecular Weight: 139kDa.

G蛋白偶联受体124抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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