G蛋白偶联受体激酶6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  G蛋白偶联受体激酶6抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves  G蛋白偶联受体激酶6抗体phosphorylation of the receptor by two classes of enzymes. The first class is comprised of the second messenger-regulated kinases, such as c-AMP dependent protein kinase A and protein kinase C. The second class includes the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of Beta-adrenergic receptor kinase: GRK 2 (Beta ARK, Beta ARK1) and GRK 3 (Beta ARK2),  G蛋白偶联受体激酶6抗体IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.

Also known as:

GRK 6; GRK-6; G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled G蛋白偶联受体激酶6抗体 receptor kinase 6; G protein-coupled receptor kinase GRK6; G-protein-coupled receptor kinase 6; Gprk6; Grk6; GRK6_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human GRK6.

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Predicted Molecular Weight: 66kDa.

 G蛋白偶联受体激酶6抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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