G蛋白偶联受体结合蛋白α11/Gα 11 抗体

Quantity size:

0.2ml

Concentration:

1mg/ml G蛋白偶联受体结合蛋白α11/Gα 11 抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter)G蛋白偶联受体结合蛋白α11/Gα 11 抗体 while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors.G蛋白偶联受体结合蛋白α11/Gα 11 抗体 Four distinct classes of Ga subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gq class includes G alpha 15, G alpha 14, G alpha 11 and G alpha q, two of which, G alpha 11 and G alphaq, are abundant in brain and lung and present at lower levels in a variety of tissues (6).

G蛋白偶联受体结合蛋白α11/Gα 11 抗体Also known as:

G alpha-11; G-protein subunit alpha-11; GNA11; GNA11_HUMAN; Guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human GNA11.

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Predicted Molecular Weight: 42kDa.

G蛋白偶联受体结合蛋白α11/Gα 11 抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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