脊髓性肌萎缩症蛋白Gemin4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 脊髓性肌萎缩症蛋白Gemin4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, 脊髓性肌萎缩症蛋白Gemin4抗体Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.

脊髓性肌萎缩症蛋白Gemin4抗体Also known as:

Gemin4; Gemin-4; Component of gems 4; Gem associated protein 4; HC56; HHRF 1; GEMI4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human,脊髓性肌萎缩症蛋白Gemin4抗体 Mouse, Rat, Dog, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human Gemin 4.

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Predicted Molecular Weight: 120kDa.

脊髓性肌萎缩症蛋白Gemin4抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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