γ-衔接蛋白相关蛋白2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  γ-衔接蛋白相关蛋白2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

A family of proteins, the GGAs (Golgi-localized, g-adaptin ear-containing, ARF-binding proteins) sequences that showed significant homology to the carboxy-terminal 'ear' domain of g-adaptin. Members of the GGA family (GGA1,GGA2 (also known as VEAR or VHS domain and ear domain of g-adaptin) and GGA3) are ubiquitous coat proteins that facilitate the trafficking of proteins between the trans-Golgi network and the lysosome. However, unlike g-adaptin, the GGAs are not associated with clathrin-coated vesicles γ-衔接蛋白相关蛋白2抗体or with any of the components of the AP-1 complex. GGA1 and GGA2 are also not associated with each other, although they colocalize on perinuclear membranes. GGA2 shares 45% amino acid sequence identity with GGA1 and 35% with GGA3. In addition to being involved in heterotypic vesicle/suborganelle interactions associated with the Golgi complex, GGA2 may have a tissue-specific function and is highly expressed in kidney, muscle and heart. Furthermore, the VHS domain of GGA2 binds to the acidic cluster-di-leucine motif in the cytoplasmic tail of the cation-independent mannose 6-phosphate receptor (CI-MPR) and this is important for lysosomal enzyme targeting.

γ-衔接蛋白相关蛋白2抗体Also known as:

1200007E24Rik; ADP ribosylation factor binding protein 2; ADP ribosylation factor binding protein GGA 2; ADP ribosylation factor binding protein GGA2; ADP-ribosylation factor-binding protein GGA2; ARF-binding protein 2; FLJ20966; Gamma adaptin related protein 2; gamma ear-containing; Gamma-adaptin-related protein 2; GGA 2; Gga2; GGA2_HUMAN; Golgi associated gamma adaptin ear containing ARF binding protein 2; Golgi localized gamma ear γ-衔接蛋白相关蛋白2抗体containing ARF binding protein 2; Golgi-localized; KIAA1080; Vear; VHS domain and ear domain containing protein; VHS domain and ear domain of gamma adaptin; VHS d

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human GGA2.

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Predicted Molecular Weight: 67kDa.

γ-衔接蛋白相关蛋白2抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl088Ca01单核细胞趋化蛋白2(MCP2)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 2 (MCP2)

kl088Eq01单核细胞趋化蛋白2(MCP2)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 2 (MCP2)

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kl089Hu01单核细胞趋化蛋白3(MCP3)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3)

kl089Mu01单核细胞趋化蛋白3(MCP3)多克隆抗体Polyclonal Antibody to Monocyte Chemotactic Protein 3 (MCP3)

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