供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL13386R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 胰岛葡萄糖6磷酸酶2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-∫,胰岛葡萄糖6磷酸酶2抗体 contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of 胰岛葡萄糖6磷酸酶2抗体IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.
Also known as:
G 6 Pase 2; G 6 Pase2; G6Pase 2; G6Pase2; G6PC 2; G6pc rs; G6pcrs; Glucose 6 phosphatase 2; Glucose 6 phosphatase, catalytic, 2; Glucose 6 phosphatase, catalytic, related; Glucose 6 胰岛葡萄糖6磷酸酶2抗体phosphate catalytic 2; Islet specific G6CP related protein; Islet specific glucose 6 phosphatase; Islet specific glucose 6 phosphatase catalytic subunit related protein; G6PC2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Glucose .
●
胰岛葡萄糖6磷酸酶2抗体Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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