糖皮质激素调节元件结合蛋白1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 糖皮质激素调节元件结合蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication.糖皮质激素调节元件结合蛋白1抗体 In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

糖皮质激素调节元件结合蛋白1抗体Also known as:

DNA binding protein p96PIF; DNA-binding protein p96PIF; Glucocorticoid modulatory element binding protein 1; Glucocorticoid modulatory element-binding protein 1; GMEB 1; GMEB-1; Gmeb1; GMEB1_HUMAN; P96PIF; Parvovirus initiation factor p96; PIF 96; PIF p96; PIF96.

Specificity:

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Rabbit Polyclonal IgG,糖皮质激素调节元件结合蛋白1抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human GMEB1.

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Predicted Molecular Weight: 63kDa.

糖皮质激素调节元件结合蛋白1抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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