通用转录因子2H亚基2C/TFIIH p44抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 通用转录因子2H亚基2C/TFIIH p44抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB,通用转录因子2H亚基2C/TFIIH p44抗体 TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of 5 subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34 . Additional subunits of the TFIIH 通用转录因子2H亚基2C/TFIIH p44抗体complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

通用转录因子2H亚基2C/TFIIH p44抗体Also known as:

General transcription factor IIH polypeptide 2-like protein; General transcription factor IIH polypeptide 2C; General transcription factor IIH subunit 2-like protein; GTF2H2D; T2H2L_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human GTF2H2C.

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通用转录因子2H亚基2C/TFIIH p44抗体Predicted Molecular Weight: 44kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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