谷氨酸受体2+谷氨酸受体3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 谷氨酸受体2+谷氨酸受体3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation谷氨酸受体2+谷氨酸受体3抗体 channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective 谷氨酸受体2+谷氨酸受体3抗体GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]

Also known as:

AMPA selective glutamate receptor 2; GRIA2_HUMAN; GRIA2_HUMAN; AMPA selective glutamate receptor 3; Ionotropic glutamate receptor 2 + 3; G protein coupled receptor family C group 1 member B; G protein coupled receptor family C group 1 member C; GluR B; GluR C;谷氨酸受体2+谷氨酸受体3抗体 GluR K2; GluR K3; GLUR3; GLURB; GLURC; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; Glutamate receptor ionotropic AMPA 2; Glutamate receptor ionotropic AMPA 3; GRIA2; GRIA3; mGluR7.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, .

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Immunogen: KLH conjugated synthetic peptide derived from human GLUR2 + .

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谷氨酸受体2+谷氨酸受体3抗体Predicted Molecular Weight: 96/98kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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