磷酸化组蛋白去乙酰化酶4/5/7抗体

Quantity size:

0.1ml

Concentration:

1mg/ml  磷酸化组蛋白去乙酰化酶4/5/7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to  磷酸化组蛋白去乙酰化酶4/5/7抗体the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes.  磷酸化组蛋白去乙酰化酶4/5/7抗体This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

 磷酸化组蛋白去乙酰化酶4/5/7抗体Also known as:

HDAC4(Phospho-Ser246); HDAC5(Phospho-Ser259); HDAC7(Phospho-Ser155); HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; p-HDAC4(Ser246); p-HDAC5(Ser259); p-HDAC7(Ser155).

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.

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 磷酸化组蛋白去乙酰化酶4/5/7抗体Predicted Molecular Weight: 119kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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