乙酰化和磷酸化组蛋白H3抗体

Quantity size:

0.1ml

Concentration:

1mg/ml  乙酰化和磷酸化组蛋白H3抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation 乙酰化和磷酸化组蛋白H3抗体and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

乙酰化和磷酸化组蛋白H3抗体Also known as:

Histone H3 (phospho S10, acetyl K9); Acetyl and phospho-Histone H3 (Ac-K9/p-Ser10); Histone H3 (Ac-K9/p-Ser10); Histone H3 (Acetyl-K9/phospho-Ser10); Histone H3 (Ac-Lys9/p-Ser10); Histone H3 (Acetyl-Lys9/phospho-Ser10); H3 histone family member E pseudogene; H3F3; HIST3H3; Histone H3 3 pseudogene; H31_TETTH; Histone H3; H3S; Histone H3-I/H3-II; Major histone H3; H3F.

Specificity:

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Rabbit Polyclonal IgG,乙酰化和磷酸化组蛋白H3抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, Fruit Fly, .

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Immunogen: KLH conjugated synthetic peptide derived from human Histone .

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Predicted Molecular Weight: 15kDa.

乙酰化和磷酸化组蛋白H3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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