供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL4281R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 疱疹病毒相关泛素特异性蛋白酶7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression疱疹病毒相关泛素特异性蛋白酶7抗体 and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection.
疱疹病毒相关泛素特异性蛋白酶7抗体Also known as:
Deubiquitinating enzyme 7; herpes virus associated; Herpes virus associated ubiquitin specific protease; Herpesvirus-associated ubiquitin-specific protease; TEF 1; tef-1; TEF1; Ubiquitin carboxyl terminal hydrolase 7; Ubiquitin carboxyl-terminal hydrolase 7; Ubiquitin specific peptidase 7 (herpes virus associated); Ubiquitin specific peptidase 7; Ubiquitin specific peptidase 7 herpes virus associated; Ubiquitin specific疱疹病毒相关泛素特异性蛋白酶7抗体 processing protease 7; Ubiquitin Specific Protease 7; Ubiquitin specific protease 7 herpes virus associated; Ubiquitin thioesterase 7; ubiquitin thiolesterase 7; Ubiquitin-spec
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human HAUSP/US.
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疱疹病毒相关泛素特异性蛋白酶7抗体Predicted Molecular Weight: 128kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl067Hu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl067Mu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl067Ra01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)
kl068Hu01多药耐药关联蛋白1(MRP1)多克隆抗体Polyclonal Antibody to Multidrug Resistance Associated Protein 1 (MRP1)
kl070Ca01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Hu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Mu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Po01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl070Ra01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)
kl072Hu01泛素连接酶E3A(UBE3A)多克隆抗体Polyclonal Antibody to Ubiquitin Protein Ligase E3A (UBE3A)
kl073Hu01白介素12受体β2(IL2Rβ2)多克隆抗体Polyclonal Antibody to Interleukin 12 Receptor Beta 2 (IL12Rb2)
kl074Bo01多聚免疫球蛋白受体(PIGR)多克隆抗体Polyclonal Antibody to Polymeric Immunoglobulin Receptor (PIGR)
kl074Hu01多聚免疫球蛋白受体(PIGR)多克隆抗体Polyclonal Antibody to Polymeric Immunoglobulin Receptor (PIGR)
kl074Mu01多聚免疫球蛋白受体(PIGR)多克隆抗体Polyclonal Antibody to Polymeric Immunoglobulin Receptor (PIGR)
kl075Hu01促胰液素(SCT)多克隆抗体Polyclonal Antibody to Secretin (SCT)
kl075Mu01促胰液素(SCT)多克隆抗体Polyclonal Antibody to Secretin (SCT)
kl077Hu01ⅡD组磷脂酶A2(PLA2G2D)多克隆抗体Polyclonal Antibody to Phospholikle A2, Group IID (PLA2G2D)
kl077Mu01ⅡD组磷脂酶A2(PLA2G2D)多克隆抗体Polyclonal Antibody to Phospholikle A2, Group IID (PLA2G2D)
kl078Hu01S100钙结合蛋白A13(S100A13)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein A13 (S100A13)
kl079Mu01通用转录因子ⅡH肽1(GTF2H1)多克隆抗体Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 1 (GTF2H1)
kl080Hu01S100钙结合蛋白A12(S100A12)多克隆抗体Polyclonal Antibody to S100 Calcium Binding Protein A12 (S100A12)
kl081Hu0170kDa热休克蛋白1A(HSPA1A)多克隆抗体Polyclonal Antibody to Heat Shock 70kDa Protein 1A (HSPA1A)
kl081Po0170kDa热休克蛋白1A(HSPA1A)多克隆抗体Polyclonal Antibody to Heat Shock 70kDa Protein 1A (HSPA1A)
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