肝癌相关抗原57抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  肝癌相关抗原57抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L. These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70. They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity. Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin 肝癌相关抗原57抗体C and TNF alpha. A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis. Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, while activation of caspase 8 is unaffected. It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities. Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals.

肝癌相关抗原57抗体Also known as:

DnaJ (Hsp40) homolog subfamily A member 3; DnaJ homolog subfamily A member 3 mitochondrial precursor; DnaJ protein Tid 1; DnaJ protein Tid1; HCA57; Hepatocellular carcinoma associated antigen 57; Highly similar to HYPOTHETICAL 105.9 KD PROTEIN F22B7.5 IN CHROMOSOME; hTid 1; hTid1; III [Caenorhabditis elegans]; TID1; Tumorous imaginal discs (Drosophila) homolog; Tumorous imaginal discs protein Tid56 homolog; DNJA3_HUMAN.

Specificity:

●

Rabbit Polyclonal IgG,肝癌相关抗原57抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human TID1/HCA.

●

肝癌相关抗原57抗体Predicted Molecular Weight: 52kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl297Hu01核糖核酸酶A(RNASE1)多克隆抗体Polyclonal Antibody to Ribonuclease A (RNASE1)

kl762Hu01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)

kl762Mu01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)

kl762Ra01磷酸化酶激酶β(PHKβ)多克隆抗体Polyclonal Antibody to Phosphorylase Kinase Beta (PHKb)

kl178Hu01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)

kl178Mu01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)

kl178Ra01α2-HS糖蛋白(αHSG)多克隆抗体Polyclonal Antibody to Alpha-2-Heremans Schmid Glycoprotein (aHSG)

kl545Hu01免疫球蛋白E(IgE)多克隆抗体Polyclonal Antibody to Immunoglobulin E (IgE)

kl545Mu01免疫球蛋白E(IgE)多克隆抗体Polyclonal Antibody to Immunoglobulin E (IgE)

kl545Ra01免疫球蛋白E(IgE)多克隆抗体Polyclonal Antibody to Immunoglobulin E (IgE)

kl436Hu01肌球蛋白ⅠG(MYO1G)多克隆抗体Polyclonal Antibody to Myosin IG (MYO1G)

kl436Mu01肌球蛋白ⅠG(MYO1G)多克隆抗体Polyclonal Antibody to Myosin IG (MYO1G)

kl436Ra01肌球蛋白ⅠG(MYO1G)多克隆抗体Polyclonal Antibody to Myosin IG (MYO1G)

kl435Hu01肌球蛋白ⅠF(MYO1F)多克隆抗体Polyclonal Antibody to Myosin IF (MYO1F)

kl435Mu01肌球蛋白ⅠF(MYO1F)多克隆抗体Polyclonal Antibody to Myosin IF (MYO1F)

kl435Ra01肌球蛋白ⅠF(MYO1F)多克隆抗体Polyclonal Antibody to Myosin IF (MYO1F)

kl434Hu01肌球蛋白ⅠE(MYO1E)多克隆抗体Polyclonal Antibody to Myosin IE (MYO1E)

kl434Mu01肌球蛋白ⅠE(MYO1E)多克隆抗体Polyclonal Antibody to Myosin IE (MYO1E)

kl434Ra01肌球蛋白ⅠE(MYO1E)多克隆抗体Polyclonal Antibody to Myosin IE (MYO1E)

kl433Hu01肌球蛋白ⅠD(MYO1D)多克隆抗体Polyclonal Antibody to Myosin ID (MYO1D)

kl433Mu01肌球蛋白ⅠD(MYO1D)多克隆抗体Polyclonal Antibody to Myosin ID (MYO1D)

kl432Hu01肌球蛋白ⅠC(MYO1C)多克隆抗体Polyclonal Antibody to Myosin IC (MYO1C)