3-羟氨苯甲酸双加氧酶抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 3-羟氨苯甲酸双加氧酶抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN),3-羟氨苯甲酸双加氧酶抗体 and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.

3-羟氨苯甲酸双加氧酶抗体Also known as:

3 HAO; 3 hydroxyanthranilate 3 4 dioxygenase; 3 hydroxyanthranilate dioxygenase; 3 hydroxyanthranilate oxygenase; 3 hydroxyanthranilic acid dioxygenase; 3-HAO; 3-hydroxyanthranilate 3; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid dioxygenase; 3HAO_HUMAN; 4-dioxygenase; haao; HAD; HAO.

Specificity:

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Rabbit Polyclonal IgG,3-羟氨苯甲酸双加氧酶抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human HAAO.

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3-羟氨苯甲酸双加氧酶抗体Predicted Molecular Weight: 33kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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