磷酸化组蛋白去乙酰化酶4(Ser246)抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化组蛋白去乙酰化酶4(Ser246)抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs磷酸化组蛋白去乙酰化酶4(Ser246)抗体 to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

磷酸化组蛋白去乙酰化酶4(Ser246)抗体Also known as:

HDAC4(Phospho-Ser246); HDAC4(Phospho-S246); p-HDAC4(Ser246); p-HDAC4(S246); HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; HDA4_CAEEL; Histone deacetylase 4; CeHDA-7; Histone deacetylase 7.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化组蛋白去乙酰化酶4(Ser246)抗体affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human.

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Predicted Molecular Weight: 119kDa.

磷酸化组蛋白去乙酰化酶4(Ser246)抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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