丙型肝炎病毒-NS3 + NS4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 丙型肝炎病毒-NS3 + NS4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HCV is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural protein necessary for viral replication. Several  丙型肝炎病毒-NS3 + NS4抗体different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity  丙型肝炎病毒-NS3 + NS4抗体through an interaction with gC1qR. The NS3 serine proteinase (NS3P) is a non-structural hepatitis C protein responsible for proteolytic processing of other non-structural proteins; because of this, it is also the most extensively studied protein of the Hepatitis C genome.

 丙型肝炎病毒-NS3 + NS4抗体Also known as:

helicase NS3; Heptatitis C Virus NS3/NS4; Non structural protein 4A; Non structural protein 4B; NS3P; NS4A; NS4B; NTPase; p27; p70; p8; Serine protease.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Hepatitis C Virus.

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Immunogen: Recombinant full length protein - polypeptide containing Hep.

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 丙型肝炎病毒-NS3 + NS4抗体Predicted Molecular Weight: 20kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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