热休克因子蛋白5抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 热休克因子蛋白5抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HSF5 is a 596 amino acid protein that localizes to the nucleus and is thought to function as a transcription factor. Multiple isoforms of HSF5 exist due to alternative splicing events. The gene encoding HSF5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary 热休克因子蛋白5抗体for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.热休克因子蛋白5抗体 Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Also known as:

FLJ40311; Heat shock factor protein 5; Heat shock transcription factor 5; Heat shock transcription factor family member 5; HSF 5; HSF5; HSF5_HUMAN; HSTF 5; MGC134827.

Specificity:

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Rabbit Polyclonal IgG,热休克因子蛋白5抗体 affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human HSF5.

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Predicted Molecular Weight: 65kDa.

热休克因子蛋白5抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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