异质核糖核蛋白A0抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 异质核糖核蛋白A0抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP 异质核糖核蛋白A0抗体proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however, some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB), and its homolog hnRNP L, bind to the 3' end of introns to modulate alternative splicing 异质核糖核蛋白A0抗体mechanisms of pre-mRNAs in normal cells and the translation of sev-eral viruses, including hepatitis C virus (HCV). The human hnRNP I gene maps to chromosome 19p13.3 and encodes a protein that is localized in the nucleoplasm. hnRNP L, like hnRNP I, is also localized in the nucleoplasm.

异质核糖核蛋白A0抗体Also known as:

HNRNPA0; Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; ROA0_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Gorilla, Marmoset (common).

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Immunogen: KLH conjugated synthetic peptide derived from human hnRNP A0.

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Predicted Molecular Weight: 31kDa.

异质核糖核蛋白A0抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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