磷酸化异染色质蛋白1抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化异染色质蛋白1抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a磷酸化异染色质蛋白1抗体 conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.

磷酸化异染色质蛋白1抗体Also known as:

HP1 alpha (phospho S92); p-HP1 alpha (phospho S92); Antigen p25; Cbx 5; CBX5; CBX5_HUMAN; CG8409; Chromobox homolog 5 (Drosophila HP1 alpha); Chromobox homolog 5 (HP1 alpha homolog Drosophila); Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog 磷酸化异染色质蛋白1抗体alpha; HP 1; HP 1A; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha; HP1Hs-alpha; Su(var)205.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthesised phosphopeptide derived from human.

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磷酸化异染色质蛋白1抗体Predicted Molecular Weight: 22kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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