热休克蛋白82抗体

Quantity size:

0.2ml

Concentration:

1mg/ml热休克蛋白82抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor binding protein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor热休克蛋白82抗体  involved in the HS response. During HS response, HSF1 undergoes conformational transition from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity.热休克蛋白82抗体  Overexpression of HSBP1 in mammalian cells represses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe effects on survival of the animals after thermal and chemical stress consistent with a role of HSBP1 as a negative regulator of heat shock response. [provided by RefSeq, Jul 2008]

热休克蛋白82抗体 Also known as:

82 kDa heat shock cognate protein; ATP-dependent molecular chaperone HSC82; Heat shock protein Hsp90 constitutive isoform.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Saccharomyces cerevisiae.

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Immunogen: KLH conjugated synthetic peptide derived from human HSC82.

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Predicted Molecular Weight: 81kDa.

热休克蛋白82抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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