供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL17538R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 人类组织相容性抗原HLA B7抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.人类组织相容性抗原HLA B7抗体 Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
人类组织相容性抗原HLA B7抗体Also known as:
Abacavir hypersensitivity, susceptibility to; Drug-induced liver injury due to flucloxacillin; HLA B; HLA class I histocompatibility antigen B 7 alpha chain; HLA class I histocompatibility antigen, B-13 alpha chain; HLA class I histocompatibility antigen, B-14 alpha chain; HLA class I histocompatibility antigen, B-15 alpha chain; HLA class I histocompatibility antigen, B-18 alpha chain; HLA class I histocompatibility 人类组织相容性抗原HLA B7抗体antigen, B-27 alpha chain; HLA class I histocompatibility antigen, B-35 alpha chain; HLA class I histocompatibility antigen, B-37 alpha chain; HLA class I hi
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, .
●
Immunogen: KLH conjugated synthetic peptide derived from human HLA B7.
●
Predicted Molecular Weight: 40kDa.
人类组织相容性抗原HLA B7抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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