组织相容性抗原DQB2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 组织相容性抗原DQB2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells 组织相容性抗原DQB2抗体(APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not 组织相容性抗原DQB2抗体thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010]

Also known as:

DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)); DX-beta; HLA class II histocompatibility antigen, DQ beta 2 chain; HLA class II histocompatibility antigen, 组织相容性抗原DQB2抗体DX beta chain; HLA DQB1; HLA DXB; major histocompatibility complex, class II, DQ beta 1; Major histocompatibility complex, class II, DQ beta 2; Major histocompatibility complex, class II, DX beta; MHC class II antigen DQB2.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human HLA-DQB2.

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组织相容性抗原DQB2抗体Predicted Molecular Weight: 27kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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