组织相容性抗原DQA1/DQA2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 组织相容性抗原DQA1/DQA2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B 组织相容性抗原DQA1/DQA2抗体 Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008]

组织相容性抗原DQA1/DQA2抗体 Also known as:

CD; CELIAC1; DC-1 alpha; DC-1 alpha chain; DQ-A1; DX alpha chain; DX-ALPHA; FLJ27088; FLJ27328; GSE; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ alpha 2 chain; HLA class II histocompatibility antigen, DQ(6) alpha chain; HLA class II histocompatibility antigen, DQ(W3) alpha chain; HLA-DCA; HLA-DQA; HLA-DQA2; HLA-DXA; leucocyte antigen DQA1; leukocyte antigen alpha chain;组织相容性抗原DQA1/DQA2抗体  major histocompatibility complex, class II, DQ alpha 1; major histocompatibility complex, class II, DQ alpha 2; MGC149527;

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Chimpanzee, Cynomolgus Monkey.

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组织相容性抗原DQA1/DQA2抗体 Immunogen: KLH conjugated synthetic peptide derived from human HLADQA1 .

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Predicted Molecular Weight: 26kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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