磷酸化神经性舞蹈病蛋白抗体

Quantity size:

0.1ml

Concentration:

1mg/ml磷酸化神经性舞蹈病蛋白抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range in the number of trinucleotide repeats has been identified in normal controls, and repeat numbers in excess of 40 have 磷酸化神经性舞蹈病蛋白抗体been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed. The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but 磷酸化神经性舞蹈病蛋白抗体may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. This gene contains an upstream open reading frame in the 5' UTR that inhibits expression of the huntingtin gene product through translational repression. [provided by RefSeq, Jul 2008]

磷酸化神经性舞蹈病蛋白抗体Also known as:

Huntingtin (phospho S421); p-Huntingtin (phospho S421); phospho-Huntingtin (Ser419); Huntingtin (phospho Ser419); Huntingtin (phospho S419); AI256365; C430023I11Rik; HD; HD protein; HD_HUMAN; HDH; HTT; Huntingtin; HUNTINGTON CHOREA; Huntington disease protein; IT 15; IT15; OTTMUSP00000026909; ZHD.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, .

●

Immunogen: KLH conjugated synthesised phosphopeptide derived from human.

●

磷酸化神经性舞蹈病蛋白抗体Predicted Molecular Weight: 348kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl350Mu01Ⅰ型胶原α1(COL1α1)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)

kl350Ra01Ⅰ型胶原α1(COL1α1)多克隆抗体Polyclonal Antibody to Collagen Type I Alpha 1 (COL1a1)

kl357Hu01成纤维细胞生长因子5(FGF5)多克隆抗体Polyclonal Antibody to Fibroblast Growth Factor 5 (FGF5)

kl362Hu01尾加压素2(UST2)多克隆抗体Polyclonal Antibody to Urotensin 2 (UST2)

kl363Hu01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)

kl363Mu01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)

kl363Ra01血小板内皮细胞粘附分子1(PECAM1)多克隆抗体Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)

kl370Hu01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)

kl370Mu01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)

kl370Ra01β-血小板球蛋白(βTG)多克隆抗体Polyclonal Antibody to Beta-Thromboglobulin (bTG)

kl371Bo0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl371Ca0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl371Hu0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl371Mu0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl371Ra0110kDa干扰素γ诱导蛋白(IP10)多克隆抗体Polyclonal Antibody to Interferon Gamma Induced Protein 10kDa (IP10)

kl373Hu01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl373Mu01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl373Ra01结蛋白(Des)多克隆抗体Polyclonal Antibody to Desmin (Des)

kl374Ra01GATA结合蛋白4(GATA4)多克隆抗体Polyclonal Antibody to GATA Binding Protein 4 (GATA4)

kl376Hu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl376Mu01辅肌动蛋白α2(ACTN2)多克隆抗体Polyclonal Antibody to Actinin Alpha 2 (ACTN2)

kl380Bo01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Hu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)

kl380Mu01血管活性肠肽(VIP)多克隆抗体Polyclonal Antibody to Vasoactive Intestinal Peptide (VIP)