HER2抗体

Quantity size:

0.1ml

Concentration:

1mg/mlHER2抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family HER2抗体 members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported HER2抗体 in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].

Also known as:

Erb-B2 Receptor Tyrosine Kinase 2; HER2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 HER2抗体 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185erbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic L

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Dog, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human C-erbB-2.

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HER2抗体 Predicted Molecular Weight: 138kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl723Hu01含MANSC域蛋白1(MANSC1)多克隆抗体Polyclonal Antibody to MANSC Domain Containing Protein 1 (MANSC1)

kl952Hu01NADH脱氢酶5(ND5)多克隆抗体Polyclonal Antibody to NADH Dehydrogenase 5 (ND5)

kl618Hu01甘露糖受体C1样蛋白1(MRC1)多克隆抗体Polyclonal Antibody to Mannose Receptor C Type 1 Like Protein 1(MRC1)

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kl653Hu01CD200受体2(CD200R2)多克隆抗体Polyclonal Antibody to CD200 Receptor 2 (CD200R2)

kl758Mu01糖化溶酶体膜蛋白(GLMP)多克隆抗体Polyclonal Antibody to Glycosylated Lysosomal Membrane Protein (GLMP)

kl844Hu01血管紧张素1-9(Ang1-9)多克隆抗体Polyclonal Antibody to Angiotensin 1-9 (Ang1-9)

kl207Hu01半乳糖凝集素9B(GAL9B)多克隆抗体Polyclonal Antibody to Galectin 9B (GAL9B)

kl491Hu01含动力蛋白重链域蛋白1(DNHD1)多克隆抗体Polyclonal Antibody to Dynein Heavy Chain Domain Containing Protein 1 (DNHD1)

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