胰岛素受体α抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 胰岛素受体α抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Insulin receptor binds insulin and has a tyrosine-protein kinase activity. It also has catalytic activity: ATP + a protein tyrosine = ADP + proteintyrosine phosphate. Tetramer of 2 alpha and 2 beta 胰岛素受体α抗体 chains linked by disulfidebonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Interacts with SORBS1 but dissociates from it following insulin stimulation. [subcellular location] Type I membrane protein. Belongs to the Tyr protein kinase family. Insulin receptor subfamily.

胰岛素受体α抗体 Also known as:

CD220; CD220 antigen; HHF5; HIR A; INSR alpha; INSR; Insulin receptor; Insulin receptor subunit alpha; IR; INSR_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 胰岛素受体α抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human Insulin .

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胰岛素受体α抗体 Predicted Molecular Weight: 80kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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