供货周期: | 现货 |
品牌: | 康朗生物 |
规格: | 0.1ml/0.2ml |
货号: | KL0162R |
CAS号: |
Quantity size:
0.2ml
Concentration:
1mg/ml 一氧化氮合成酶-2(诱导型)抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) &一氧化氮合成酶-2(诱导型)抗体 endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. Nitric oxide synthase is expressed in liver, macrophages, hepatocytes, synoviocytes, stimulated glial cells and smooth muscle cells. Cytokines such as interferon-gamma (IFN), 一氧化氮合成酶-2(诱导型)抗体tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOS2).
Also known as:
i NOS; Nitric Oxide Synthase, Inducible; HEP NOS; Hepatocyte NOS; HEPNOS; Inducible nitric oxide synthase; Inducible NO synthase; Inducible NOS; INOS; Inosl; MAC NOS; Macrophage NOS; Nitric oxide synthase 一氧化氮合成酶-2(诱导型)抗体2 inducible macrophage; Nitric oxide synthase 2A (inducible hepatocytes); Nitric oxide synthase inducible; NOS 2; NOS 2A; NOS; Nos II; NOS type II; Nos2; NOS2A; NOS2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, .
●
Immunogen: KLH conjugated synthetic peptide derived from human NOS-2.
●
一氧化氮合成酶-2(诱导型)抗体Predicted Molecular Weight: 130kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl583Ra01水通道蛋白5(AQP5)多克隆抗体Polyclonal Antibody to Aquaporin 5 (AQP5)
kl584Hu01血红素氧合酶1(HO1)多克隆抗体Polyclonal Antibody to Heme Oxygenase 1, Decycling (HO1)
kl584Mu01血红素氧合酶1(HO1)多克隆抗体Polyclonal Antibody to Heme Oxygenase 1, Decycling (HO1)
kl584Ra01血红素氧合酶1(HO1)多克隆抗体Polyclonal Antibody to Heme Oxygenase 1, Decycling (HO1)
kl585Hu01细胞周期素D1(CCND1)多克隆抗体Polyclonal Antibody to Cyclin D1 (CCND1)
kl585Mu01细胞周期素D1(CCND1)多克隆抗体Polyclonal Antibody to Cyclin D1 (CCND1)
kl585Ra01细胞周期素D1(CCND1)多克隆抗体Polyclonal Antibody to Cyclin D1 (CCND1)
kl586Hu01细胞周期素D2(CCND2)多克隆抗体Polyclonal Antibody to Cyclin D2 (CCND2)
kl588Hu01M2-型丙酮酸激酶(PKM2)多克隆抗体Polyclonal Antibody to Pyruvate Kinase, Muscle (PKM2)
kl588Mu01M2-型丙酮酸激酶(PKM2)多克隆抗体Polyclonal Antibody to Pyruvate Kinase, Muscle (PKM2)
kl588Ra01M2-型丙酮酸激酶(PKM2)多克隆抗体Polyclonal Antibody to Pyruvate Kinase, Muscle (PKM2)
kl589Hu01血红素氧合酶2(HO2)多克隆抗体Polyclonal Antibody to Heme Oxygenase 2, Decycling (HO2)
kl589Ra01血红素氧合酶2(HO2)多克隆抗体Polyclonal Antibody to Heme Oxygenase 2, Decycling (HO2)
kl593Hu01肌原纤蛋白1(FBN1)多克隆抗体Polyclonal Antibody to Fibrillin 1 (FBN1)
kl593Ra01肌原纤蛋白1(FBN1)多克隆抗体Polyclonal Antibody to Fibrillin 1 (FBN1)
kl598Ra01微粒体谷胱甘肽S转移酶2(MGST2)多克隆抗体Polyclonal Antibody to Microsomal Glutathione S Transferase 2 (MGST2)
kl599Mu01颗粒酶A(GZMA)多克隆抗体Polyclonal Antibody to Granzyme A (GZMA)
kl600Hu01颗粒酶B(GZMB)多克隆抗体Polyclonal Antibody to Granzyme B (GZMB)
kl600Mu01颗粒酶B(GZMB)多克隆抗体Polyclonal Antibody to Granzyme B (GZMB)
kl600Ra01颗粒酶B(GZMB)多克隆抗体Polyclonal Antibody to Granzyme B (GZMB)
kl601Bo01髓过氧化物酶(MPO)多克隆抗体Polyclonal Antibody to Myeloperoxidase (MPO)
kl601Eq01髓过氧化物酶(MPO)多克隆抗体Polyclonal Antibody to Myeloperoxidase (MPO)
kl601Po01髓过氧化物酶(MPO)多克隆抗体Polyclonal Antibody to Myeloperoxidase (MPO)
相关产品
关注
拨打电话
留言咨询