胰岛素样生长因子结合蛋白4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 胰岛素样生长因子结合蛋白4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Insulin like growth factor binding protein 4 (IGFBP4) is produced from a DNA sequence encoding the human IGFBP4 protein. Mature human IGFBP4 has a calculated molecular mass of approximately 26 kDa. Due to glycosylation, the recombinant protein migrates as a 32 kDa and 25 kDa protein under reducing and non reducing conditions, respectively. Human 胰岛素样生长因子结合蛋白4抗体IGFBP4 has a potential N-linked glycosylation site and shares approximately 90% amino acid sequence identity with both mouse and rat IGFBP4. IGFBP4 is a member of the superfamily of insulin-like growth factor (IGF) binding proteins which include six high affinity IGF binding proteins (IGFBP) and at least four low affinity binding proteins referred 胰岛素样生长因子结合蛋白4抗体to as IGFBP related proteins (IGFBPrP). IGFBP4 functions as an inhibitor of IGF action and its main function may be to protect cells from overstimulation by IGFs or to allow activation of alternate transmembrane signaling pathways that are inhibited by IGF exposure. IGFBP4 is expressed in multiple tissues including adrenal, testis, spleen, heart, lung, kidney, liver, stomach, hypothalamus, and brain cortex.

胰岛素样生长因子结合蛋白4抗体Also known as:

Insulin-like Growth Factor Binding Protein 4; BP 4; BP4; HT29 IGFBP; IBP 4; IBP4; IGF binding protein 4; IGFBP 4; IBP4_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human IGFBP4.

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胰岛素样生长因子结合蛋白4抗体Predicted Molecular Weight: 26kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

IHC-P=1:100-500  IHC-F=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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