整合素α1抗体

Quantity size:

0.2ml

Concentration:

1mg/ml整合素α1抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low 整合素α1抗体affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton 整合素α1抗体and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.

整合素α1抗体Also known as:

CD 49a; CD49a; CD49 antigen-like family member A; CD49a; CD49a antigen; Integrin alpha-1; ITA1_HUMAN; Itga 1; ITGA1; Laminin and collagen receptor; Very late activation protein 1; VLA 1; VLA-1; VLA1.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Cow, Horse, .

●

Immunogen: KLH conjugated synthetic peptide derived from human Integrin.

●

整合素α1抗体Predicted Molecular Weight: 128kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:20-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

l026Hu01趋化因子C-C-基元配体3样蛋白1(CCL3L1)多克隆抗体Polyclonal Antibody to Chemokine C-C-Motif Ligand 3 Like Protein 1 (CCL3L1)

kl026Mu01趋化因子C-C-基元配体3样蛋白1(CCL3L1)多克隆抗体Polyclonal Antibody to Chemokine C-C-Motif Ligand 3 Like Protein 1 (CCL3L1)

kl027Hu01红细胞生成素受体(EPOR)多克隆抗体Polyclonal Antibody to Erythropoietin Receptor (EPOR)

kl027Ra01红细胞生成素受体(EPOR)多克隆抗体Polyclonal Antibody to Erythropoietin Receptor (EPOR)

kl029Bo01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Ca01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Cp01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Eq01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Hu01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Mu01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Po01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Ra01E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl029Rb51E选择素(SELE)多克隆抗体Polyclonal Antibody to Selectin, Endothelium (SELE)

kl030Bo01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl030Hu01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl030Mu01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl030Po01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl030Ra01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl030Si01凋亡相关因子(FAS)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis (FAS)

kl031Hu01凋亡相关因子配体(FASL)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis Ligand (FASL)

kl031Mu01凋亡相关因子配体(FASL)多克隆抗体Polyclonal Antibody to Factor Related Apoptosis Ligand (FASL)