整合素α6抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 整合素α6抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low 整合素α6抗体affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton整合素α6抗体 and signaling function. Integrin alpha 6 complexes are receptors for laminins, which are components of basement membranes. Integrin alpha 6 complexes may play an important role in embryogenesis.

Also known as:

Integrin alpha 6; Alpha 6; B cell associated molecule CD40; CD 49f; CD49f; ITGA6; CD40 antigen; CD40 type II isoform; CD49f; CD49f antigen; Integrin alpha chain; ITGA 6; ITGA6; ITGA6B; Nerve growth 整合素α6抗体factor receptor related B lymphocyte activation molecule; p50; Tumor necrosis factor receptor superfamily member 5 precurso; VLA 6 alpha subunit; VLA 6.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, .

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Immunogen: KLH conjugated synthetic peptide derived from human Integrin.

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整合素α6抗体Predicted Molecular Weight: 124kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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