大脑和睾丸特异性免疫球蛋白超家族成员11抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 大脑和睾丸特异性免疫球蛋白超家族成员11抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11大脑和睾丸特异性免疫球蛋白超家族成员11抗体 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations 大脑和睾丸特异性免疫球蛋白超家族成员11抗体during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.

Also known as:

brain and testis specific immunoglobin superfamily protein; BTIGSF; CXADR like 1; CXADRL1; Igsf13; 大脑和睾丸特异性免疫球蛋白超家族成员11抗体immunoglobulin superfamily member 11; Immunoglobulin superfamily member 11 precursor; MGC35227; V set and immunoglobulin domain containing 3; V set and immunoglobulin domain containing protein 3; VSIG3; IGS11_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human IGSF11.

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大脑和睾丸特异性免疫球蛋白超家族成员11抗体Predicted Molecular Weight: 44kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:50-200   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl019Mu01白介素8受体α(IL8Rα)多克隆抗体Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)

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kl021Mu01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

kl021Po01睫状神经营养因子(CNTF)多克隆抗体Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)

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