RasGTP酶激活蛋白IQGAP3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml RasGTP酶激活蛋白IQGAP3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

IQGAP3 is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons.RasGTP酶激活蛋白IQGAP3抗体  IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number ofRasGTP酶激活蛋白IQGAP3抗体  disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Also known as:

IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3 ; IQGAP3; MGC10170; MGC10831; MGC1947 RasGTP酶激活蛋白IQGAP3抗体 antibodyOTTHUMP00000031854 ; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3; Ras GTPase-activating-like protein IQGAP3.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human IQGAP3.

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RasGTP酶激活蛋白IQGAP3抗体 Predicted Molecular Weight: 185kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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