γ干扰素诱导蛋白IP30抗体

Quantity size:

0.2ml

Concentration:

1mg/ml γ干扰素诱导蛋白IP30抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process isγ干扰素诱导蛋白IP30抗体 catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively inV antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.

Also known as:

Gamma interferon inducible lysosomal thiol reductase; Gamma interferon inducible protein IP 30; GILT; IFI 30; γ干扰素诱导蛋白IP30抗体interferon gamma inducible protein 30; Interferon gamma inducible protein 30 preproprotein; IP30; Lysosomal thiol reductase; Lysosomal thiol reductase, gamma-interferon-inducible; GILT_HUMAN.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, .

●

Immunogen: KLH conjugated synthetic peptide derived from human IFI30/GI.

●

γ干扰素诱导蛋白IP30抗体Predicted Molecular Weight: 29kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl833Po01血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl833Rb51血管性血友病因子(vWF)多克隆抗体Polyclonal Antibody to Von Willebrand Factor (vWF)

kl834Hu01凝血因子Ⅹ(F10)多克隆抗体Polyclonal Antibody to Coagulation Factor X (F10)

kl834Mu01凝血因子Ⅹ(F10)多克隆抗体Polyclonal Antibody to Coagulation Factor X (F10)

kl834Ra01凝血因子Ⅹ(F10)多克隆抗体Polyclonal Antibody to Coagulation Factor X (F10)

kl837Ca01诱导型一氧化氮合酶(NOS2)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

kl837Hu01诱导型一氧化氮合酶(NOS2)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

kl837Mu01诱导型一氧化氮合酶(NOS2)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

kl837Ra01诱导型一氧化氮合酶(NOS2)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

kl837Rb51诱导型一氧化氮合酶(NOS2)多克隆抗体Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

kl838Hu01抑制素βA(INHβA)多克隆抗体Polyclonal Antibody to Inhibin Beta A (INHbA)

kl838Ra01抑制素βA(INHβA)多克隆抗体Polyclonal Antibody to Inhibin Beta A (INHbA)

kl840Hu01凝血因子Ⅸ(F9)多克隆抗体Polyclonal Antibody to Coagulation Factor IX (F9)

kl840Mu01凝血因子Ⅸ(F9)多克隆抗体Polyclonal Antibody to Coagulation Factor IX (F9)

kl840Ra01凝血因子Ⅸ(F9)多克隆抗体Polyclonal Antibody to Coagulation Factor IX (F9)

kl841Mu01含血管性血友病因子A域蛋白1(vWA1)多克隆抗体Polyclonal Antibody to Von Willebrand Factor A Domain Containing Protein 1 (vWA1)

kl842Hu01脂蛋白a(Lpa)多克隆抗体Polyclonal Antibody to Lipoprotein, a (Lpa)

kl846Bo01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl846Po01催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)

kl846Rb51催乳素(PRL)多克隆抗体Polyclonal Antibody to Prolactin (PRL)