A型流感病毒核输出蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml A型流感病毒核输出蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. A型流感病毒核输出蛋白抗体This domain is believed to allow recognition of RNPs to which the M1 protein is bound. Because the M1 protein is not available in large quantities until the later stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the nucleus before sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.A型流感病毒核输出蛋白抗体 Furthermore, the RNPs enters the cytoplasm only when they have associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced.

A型流感病毒核输出蛋白抗体Also known as:

NS1; NEP_I97A1; Nuclear export protein; NEP; Non-structural protein 2; NS2. NS1A.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Influenza A.

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Immunogen: KLH conjugated synthetic peptide derived from Influenza A In.

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A型流感病毒核输出蛋白抗体Predicted Molecular Weight: 14kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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