甲状腺受体相互作用蛋白8抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 甲状腺受体相互作用蛋白8抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

JMJD1C is a nuclear protein that belongs to the JHDM2 family of histone demethylases. Expressed in a wide variety of tissues, JMJD1C binds iron as a cofactor and contains one JMJC domain, a TRI8H1 domain with a C2HC4-type zinc finger-like motif and a TRI8H2甲状腺受体相互作用蛋白8抗体  domain with a TR∫ (thyroid hormone receptor ∫)-binding region. JMJD1C demethylates lysine-9 of Histone H3, thereby playing a central role in the histone code and participating in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1C plays an important role in the regulation of cell growth during development and in chromatin regulation. Due to alternative splicing events, two isoforms exist for JMJD1C. One of these isoforms functions as a coactivator for the AR (androgen receptor).

甲状腺受体相互作用蛋白8抗体 Also known as:

JHD2C_HUMAN; Jmjd1c; Jumonji domain containing 1C; Jumonji domain-containing protein 1C; Probable JmjC domain-containing histone demethylation protein 2C; Thryoid receptor interacting protein; Thyroid receptor-interacting protein 8; TR-interacting protein 8; TRIP-8; TRIP8.

Specificity:

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Rabbit Polyclonal IgG, affinity甲状腺受体相互作用蛋白8抗体  purified by Protein A.

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Reacts with: Human, Cow, Horse, Rabbit, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human JMJD1C.

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Predicted Molecular Weight: 284kDa.

甲状腺受体相互作用蛋白8抗体 Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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