CREB结合蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml CREB结合蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB, which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein).CREB结合蛋白抗体 These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 molecules lacking an intact E1A binding site bypass E1A repression, even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.

CREB结合蛋白抗体Also known as:

CBP; CBP/p300; CBP_HUMAN; CREB binding protein; CREB-binding protein; CREBBP; Cyclic AMP responsive enhancer binding protein; Cyclic AMP-responsive enhancer binding protein; KAT3A; RSTS; RTS; Rubinstein Taybi syndrome; Rubinstein-Taybi syndrome.

Specificity:

●

Rabbit Polyclonal IgG,CREB结合蛋白抗体 affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .

●

Immunogen: KLH conjugated synthetic peptide derived from human KAT3A/CB.

●

Predicted Molecular Weight: 265kDa.

CREB结合蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

kl050Ra01雌激素受体α(ERα)多克隆抗体Polyclonal Antibody to Estrogen Receptor Alpha (ERa)

kl051Hu01胆囊收缩素B受体(CCKBR)多克隆抗体Polyclonal Antibody to Cholecystokinin B Receptor (CCKBR)

kl053Hu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)

kl053Mu01细胞色素P450家族成员7A1(CYP7A1)多克隆抗体Polyclonal Antibody to Cytochrome P450 7A1 (CYP7A1)

kl054Hu01凋亡蛋白酶激活因子1(Akl1)多克隆抗体Polyclonal Antibody to Apoptotic Peptidase Activating Factor 1 (Akl1)

kl058Hu01胱天蛋白酶激活脱氧核糖核酸酶(CAD)多克隆抗体Polyclonal Antibody to Caskle Activated DNase (CAD)

kl059Hu01岩藻糖基转移酶4(FUT4)多克隆抗体Polyclonal Antibody to Fucosyltransferase 4 (FUT4)

kl061Hu01蛋白二硫键异构酶(PDI)多克隆抗体Polyclonal Antibody to Protein Disulfide Isomerase (PDI)

kl062Hu0170kDa热休克蛋白1样蛋白(HSPA1L)多克隆抗体Polyclonal Antibody to Heat Shock 70kDa Protein 1 Like Protein (HSPA1L)

kl063Hu01泛素结合酶E2A(UBE2A)多克隆抗体Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2A (UBE2A)

kl063Mu01泛素结合酶E2A(UBE2A)多克隆抗体Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2A (UBE2A)

kl064Hu01凋亡诱导因子(AIF)多克隆抗体Polyclonal Antibody to Apoptosis Inducing Factor (AIF)

kl064Ra01凋亡诱导因子(AIF)多克隆抗体Polyclonal Antibody to Apoptosis Inducing Factor (AIF)

kl065Hu01丙氨酸氨肽酶(AAP)多克隆抗体Polyclonal Antibody to Alanine Aminopeptidase (AAP)

kl066Hu01多巴色素异构酶(DT)多克隆抗体Polyclonal Antibody to Doklhrome Tautomerase (DCT)

kl067Hu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)

kl067Mu01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)

kl067Ra01YY肽(PYY)多克隆抗体Polyclonal Antibody to Peptide YY (PYY)

kl068Hu01多药耐药关联蛋白1(MRP1)多克隆抗体Polyclonal Antibody to Multidrug Resistance Associated Protein 1 (MRP1)

kl070Ca01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)

kl070Hu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)

kl070Mu01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)

kl070Po01类胰蛋白酶(TPS)多克隆抗体Polyclonal Antibody to Tryptase (TPS)