肾细胞癌抗原NYREN 45抗体

Quantity size:

0.2ml

Concentration:

1mg/ml肾细胞癌抗原NYREN 45抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably肾细胞癌抗原NYREN 45抗体, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons,肾细胞癌抗原NYREN 45抗体 Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

肾细胞癌抗原NYREN 45抗体Also known as:

BTB/POZ domain-containing protein KCTD3; Kctd3; KCTD3_HUMAN; MGC43935; NY REN 45; NY REN 45 antigen; NY REN45; NYREN 45; OTTHUMP00000035070; Potassium channel tetramerisation domain containing 3; Renal carcinoma antigen NY REN 45; Renal carcinoma antigen NY-REN-45.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, .

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Immunogen: KLH conjugated synthetic peptide derived from human KCTD3.

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Predicted Molecular Weight: 89kDa.

肾细胞癌抗原NYREN 45抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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