KIAA0427蛋白抗体

Quantity size:

0.2ml

Concentration:

1mg/ml KIAA0427蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAsKIAA0427蛋白抗体 toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]

KIAA0427蛋白抗体Also known as:

CBP80/20-dependent translation initiation factor; ctif; CTIF_HUMAN; Gm672; Hypothetical protein LOC9811; Uncharacterized protein KIAA0427.

Specificity:

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Rabbit Polyclonal IgG, KIAA0427蛋白抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, .

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Immunogen: KLH conjugated synthetic peptide derived from human KIAA0427.

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Predicted Molecular Weight: 68kDa.

KIAA0427蛋白抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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