驱动蛋白家族成员3C抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 驱动蛋白家族成员3C抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell (1-3). Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis驱动蛋白家族成员3C抗体 and transcytosis (3,4). Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C (5). KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis (6). The human KIF3C gene maps to chromosome 2p23 and encodes a 793 amino acid protein that is highly expressed in neural tissues such as brain, spinal cord and retina (7,8).驱动蛋白家族成员3C抗体 The selective expression of KIF3C protein in the nervous system during embryonic development and its upregulation during neuroblastoma differentiation suggests a role for this motor during maturation of neuronal cells (9).

驱动蛋白家族成员3C抗体Also known as:

KIAA4058; KIF3C; KIF3C variant protein; KIF3C_HUMAN; Kinesin family member 3C; Kinesin like protein KIF3C; Kinesin-like protein KIF3C; mKIAA4058.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, .

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Immunogen: KLH conjugated synthetic peptide derived from human KIF3C.

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Predicted Molecular Weight: 89kDa.

驱动蛋白家族成员3C抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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